Thursday, November 08, 2007

Individual Genetic Variation 5X Greater Than Thought

The First Diploid Sequence of an Individual Human: The highly accurate sequence suggests that our genetic code is five times as variable as we thought

SOURCE: "The Diploid Genome Sequence of an Individual Human" Samuel Levy et al.
PLoS Biology
5: e254

RESULTS: Genomics pioneer Craig Venter and his colleagues have generated a highly accurate sequence of Venter's genome, one that includes the DNA sequences inherited from both his mother and his father.

WHY IT MATTERS: The genome sequence generated by the Human Genome Project, the massive, distributed effort to sequence human DNA that was completed in 2003, was a milestone in the history of biology. But the DNA sequence produced by the project represented just one set of chromosomes (every human has two sets, one inherited from each parent), and it drew on DNA samples from many individuals. As a result, it didn't reflect some of the variability between individuals. ­Venter's diploid genome suggests that genetic variation between individuals is approximately 0.5 percent, not the 0.1 percent that earlier sequencing projects suggested.

METHODS: In the new study, researchers used a method of gene sequencing called Sanger sequencing. The method is more expensive than newer approaches, but it generates longer strings of DNA that are easier to assemble into a complete genome.

NEXT STEPS: Venter and his colleagues plan to add phenotypic information, such as medical records and physical characteristics, to the database housing his genome. This will allow scientists to begin analyzing an individual's genomic information in the context of his or her actual traits.

63 comments:

Anonymous said...

buy ativan ativan expected side effects - negative side effects ativan

Anonymous said...

diazepam and dosage diazepam in urine - order diazepam online canada

Anonymous said...

ativan medication ativan 1mg dosage - ativan epocrates

Anonymous said...

buy zolpidem zolpidem tartrate 10 mg tablet side effects - zolpidem tartrate zolpidem

Anonymous said...

ativan anxiety ativan get u high - ativan and xanax interaction

Anonymous said...

buy xanax online legally should buy xanax online - meloxicam xanax drug interactions

Anonymous said...

buy zolpidem online zolpidem tartrate 10 mg tablet side effects - zolpidem quality sleep

Anonymous said...

buy xanax online without prescription pills that look like xanax - 2 mg xanax too much

Anonymous said...

order xanax what does the drug xanax do to you - xanax urine drug screen

Anonymous said...

online xanax no prescription xanax side effects libido - xanax increased anxiety

Anonymous said...

buy soma 350mg carisoprodol dosage erowid - prescription drug soma used

Anonymous said...

buy ambien online buy ambien 10mg online - buy ambien online india

Anonymous said...

cheap soma carisoprodol 350 mg sleep - buy soma online ship florida

Anonymous said...

cheap generic soma buy somatropin online uk - order soma online texas

Anonymous said...

generic valium pill identifier valium medication muscle relaxer - valium and anxiety disorder

Anonymous said...

soma pain buy soma online with mastercard - carisoprodol kratom

Anonymous said...

valium drug how to buy valium online uk - cheap valium sale uk

Anonymous said...

order soma online soma drug action - where to buy soma online overnight

Anonymous said...

valium no prescription online valium erowid - buy generic valium online

Anonymous said...

Blogger: subrealism - Post a Comment cheap ventolin online - generic ventolin online http://www.ventolinforsaleonline.com/#generic-ventolin-online

Anonymous said...

Hello, propecia 5mg - finasteride without prescription http://www.bigdocpoker.com/#cheap-propecia-no-prescription

Anonymous said...

Penicillin Vk Drug Interactions acomplia 20mg - buy acomplia online no prescription http://www.buydiscountedisotretinoin.net/#buy-acomplia-online-no-prescription

Anonymous said...

Hello, cheap atorvastatin online - atorvastatin no prescription http://www.costoflipitoronline.net/#atorvastatin-no-prescription

Anonymous said...

Hello, buy lipitor - generic lipitor no prescription http://www.costoflipitoronline.net/#generic-lipitor-no-prescription

Anonymous said...

advitleva propecia 5mg - finasteride without prescription http://www.bestpricefinasteride.com/

Anonymous said...

advitleva generic finasteride - finasteride price http://www.bestpricefinasteride.com/

Anonymous said...

Hello, cytotec medication - order cytotec no prescription http://www.cytotecforlessonline.net/#order-cytotec-no-prescription

Anonymous said...

Hello, buy cytotec without prescription - cytotec pill http://www.cytotecforlessonline.net/#cytotec-pill

Anonymous said...

Palm Beach Diet Drug Lawyers buy topiramate online - generic topamax http://www.topamaxforless.com/

Anonymous said...

dalsCleax cheap accutane - accutane no prescription http://www.isotretinoinlowcost.com/#accutane-no-prescription

Anonymous said...

dalsCleax buy strattera - buy strattera online http://www.stratterabestprice.com/#buy-strattera-online

Anonymous said...

Michael Irvin Caught With Drugs buy sibutramine online - sibutramine online http://www.meridiaonlineorder.net/#sibutramine-online , [url=http://www.meridiaonlineorder.net/#sibutramine-for-sale ]sibutramine for sale [/url]

Anonymous said...

2, cheap propecia online - propecia online no prescription http://www.wheretobuymedsonline.com/propecia/], [url=http://www.wheretobuymedsonline.com/propecia/]buy finasteride no prescription [/url]

Anonymous said...

2, ambien without prescription - cheap generic ambien http://www.opensourcewcms.com/#cheap-generic-ambien , [url=http://www.opensourcewcms.com/#buy-ambien ]buy ambien [/url]

Anonymous said...

2, buy generic ambien online - ambien for sale no prescription http://www.opensourcewcms.com/#ambien-for-sale-no-prescription , [url=http://www.opensourcewcms.com/#cost-of-ambien ]cost of ambien [/url]

Anonymous said...

2, propecia without prescription - buy finasteride online no prescription http://www.propeciagenericforsale.com/#order-finasteride , [url=http://www.propeciagenericforsale.com/#buy-cheap-finasteride ]propecia pills [/url]

Anonymous said...

2, cheap stendra online - generic stendra online http://www.stendraonlinecost.com/#generic-stendra-online , [url=http://www.stendraonlinecost.com/#avanafil-online ]avanafil online [/url]

Anonymous said...

tni buy plavix online - generic clopidogrel http://www.plavixbuynow.net/#cheap-plavix, [url=http://www.plavixbuynow.net/#cheap-plavix]buy plavix without prescription [/url]

Anonymous said...

losneyfgd buy klonopin online without prescription - cheap clonazepam no prescription http://www.stationcoffeeandtea.com/#cheap-clonazepam-no-prescription , [url=http://www.stationcoffeeandtea.com/#where-to-buy-klonopin ]where to buy klonopin [/url]

Anonymous said...

x90, Maxalt No Prescription - cheap maxalt http://www.maxaltonlinerx.net/maxalt-online-pharmacy.html#Maxalt-No-Prescription, [url=http://www.maxaltonlinerx.net/maxalt-online-pharmacy.html#Maxalt-Pills]Maxalt Pills[/url]

Anonymous said...

ooo!!! Buy Topamax - topamax without prescription http://www.topamaxbestonline.net/#generic-topiramate, [url=http://www.topamaxbestonline.net/#generic-topiramate]Topamax Cost[/url]

Anonymous said...

ooo!!! Topamax For Sale - order topamax online no prescription http://www.cheaptopamaxorder.net/#buy-topiramate, [url=http://www.cheaptopamaxorder.net/#buy-topiramate]Buy Topiramate[/url]

Anonymous said...

ooo!!! Generic Topiramate - topamax cost http://www.topamaxbestonline.net/#topamax-cost, [url=http://www.topamaxbestonline.net/#topamax-cost]Topamax Online[/url]

Anonymous said...

ooo!!! Generic Topiramate - generic topamax cost http://www.topamaxbestonline.net/#order-topamax, [url=http://www.topamaxbestonline.net/#order-topamax]Generic Topiramate[/url]

Anonymous said...

ooo!!! Topamax No Prescription - topamax without prescription http://www.cheaptopamaxorder.net/#topamax-no-prescription, [url=http://www.cheaptopamaxorder.net/#topamax-no-prescription]Cheap Topamax[/url]

Anonymous said...

2013 zyban medication - buy zyban http://www.wellbutrinforsaleonline.net/, [url=http://www.wellbutrinforsaleonline.net/]cheap zyban [/url]

Anonymous said...

g, Chemistry Project - http://www.onlinewritinghelp101.com/chemistry.html#chemistry-project, [url=http://www.onlinewritinghelp101.com/chemistry.html#chemistry-online]Chemistry Online[/url]

Anonymous said...

g, price of plavix - generic plavix cost http://www.plavixonlineorder.com/#generic-plavix-cost , [url=http://www.plavixonlineorder.com/#purchase-plavix ]purchase plavix [/url]

Anonymous said...

g, cheap plavix online - clopidogrel price http://www.plavixonlineorder.com/#clopidogrel-price , [url=http://www.plavixonlineorder.com/#cheap-plavix-75-mg ]cheap plavix 75 mg [/url]

Anonymous said...

ny, vardenafil for sale - levitra without rx http://www.recoverinchrist.org/#levitra-without-rx , [url=http://www.recoverinchrist.org/#generic-levitra-20mg ]generic levitra 20mg [/url]

Anonymous said...

4, generic provigil cost - buy generic provigil http://www.provigilonlineoffer.net/, [url=http://www.provigilonlineoffer.net/]cheap provigil online [/url]

Anonymous said...

1, [url=http://www.lunestabenefits.net/] Lunesta For Sale [/url] - Generic Lunesta - lunesta medication http://www.lunestabenefits.net/.

Anonymous said...

3, cheap effexor - effexor no prescription http://www.effexorbenefits.net/, [url=http://www.effexorbenefits.net/]effexor for sale [/url]

Anonymous said...

2, [url=http://www.nexiumonlinefaq.net/]Buy Nexium[/url] - Nexium 20mg - cheap nexium http://www.nexiumonlinefaq.net/.

Anonymous said...

2, [url=http://www.doesprozacwork.net/]Prozac Sale[/url] - Buy Prozac - generic prozac no prescription http://www.doesprozacwork.net/.

Anonymous said...

buy acomplia - acomplia for sale http://www.acompliadietbenefits.net/, [url=http://www.acompliadietbenefits.net/]acomplia price[/url]

Anonymous said...

6, [url=http://www.isotretinoinonlinerx.net/] Cheap Accutane [/url] - Order Isotretinoin Online - buy accutane no prescription http://www.isotretinoinonlinerx.net/ .

Anonymous said...

6, [url=http://www.costofeffexor.net/]buy effexor [/url] - effexor cost - buy venlafaxine http://www.costofeffexor.net/.

Anonymous said...

6, [url=http://www.costofeffexor.net/]Order Effexor Online[/url] - Effexor No Prescription - venlafaxine for sale http://www.costofeffexor.net/

Anonymous said...

6, [url=http://www.cheapzoloftrx.net/] Generic Zoloft [/url] - Buy Zoloft - buy generic zoloft no prescription http://www.cheapzoloftrx.net/ .

Anonymous said...

5, [url=http://www.nexiumpricewatch.net/] Esomeprazole Online [/url] - Generic Nexium - discount nexium http://www.nexiumpricewatch.net/ .

Anonymous said...

6, [url=http://www.cheapzoloftrx.net/]sertraline online no prescription [/url] - zoloft cost - cheap zoloft http://www.cheapzoloftrx.net/.

Anonymous said...

5, [url=http://www.cheapzoloftrx.net/] Buy Zoloft Online [/url] - Zoloft For Sale - sertraline without prescription http://www.cheapzoloftrx.net/ .

When Zakharova Talks Men Of Culture Listen...,

mid.ru  |   White House spokesman John Kirby’s statement, made in Washington shortly after the attack, raised eyebrows even at home, not ...